The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody.
Anti-double-stranded (ds) DNA antibodies are not only an important diagnostic marker for SLE, but also play an important role in tissue injury. Microbial antigen may be a stimulus for the production of these antibodies. We isolated 99D.7E, an IgG2b monoclonal antibody from a nonautoimmune BALB/c mou...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118666 |
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