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Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1

The transmembrane voltage needed to open different voltage-gated K (Kv) channels differs by up to 50 mV from each other. In this study we test the hypothesis that the channels’ voltage dependences to a large extent are set by charged amino-acid residues of the extracellular linkers of the Kv channel...

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Vydáno v:Biophys J
Hlavní autoři: Elinder, Fredrik, Madeja, Michael, Zeberg, Hugo, Århem, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072986/
https://ncbi.nlm.nih.gov/pubmed/27760355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.08.043
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