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Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.

The expression of leptin, the ob gene product, is increased in adipose tissue in response to feeding and energy repletion, while leptin decreases food intake. Because adipose tissue gene expression is regulated by cytokines induced during infection and because infection is associated with anorexia,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Grunfeld, C, Zhao, C, Fuller, J, Pollack, A, Moser, A, Friedman, J, Feingold, K R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507291/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621806/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118653
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