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Leptin in Hepatic Fibrosis: Evidence for Increased Collagen Production in Stellate Cells and Lean Littermates of ob/ob Mice

Leptin is a 16-kd hormone that mediates a range of metabolic effects by using a transduction pathway from the long form of the leptin receptor, OB-R(L,) through Janus kinase–signal transducer and activator of transcription (Jak-Stat) signaling components. Leptin is produced by hepatic stellate cells...

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Detalhes bibliográficos
Main Authors: Saxena, Neeraj K., Ikeda, Kazuo, Rockey, Don C., Friedman, Scott L., Anania, Frank A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935193/
https://ncbi.nlm.nih.gov/pubmed/11915021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/jhep.2002.32029
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