Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment

Discovery of somatic mutations in the calreticulin gene (CALR) has identified a subgroup of Philadelphia-negative chronic myeloproliferative neoplasms (MPN) with separate haematological characteristics and prognosis. CALR mutations serve as novel markers both of diagnostic value and as targets for m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kjær, Lasse, Cordua, Sabrina, Holmström, Morten O., Thomassen, Mads, Kruse, Torben A, Pallisgaard, Niels, Larsen, Thomas S., de Stricker, Karin, Skov, Vibe, Hasselbalch, Hans C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072743/
https://ncbi.nlm.nih.gov/pubmed/27764253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165336
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