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Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability
In the current work, a rapid, specific, sensitive and validated liquid chromatography tandem mass-spectrometric method was developed for the quantification of ponatinib (PNT) in human plasma and rat liver microsomes (RLMs) with its application to metabolic stability. Chromatographic separation of PN...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072736/ https://ncbi.nlm.nih.gov/pubmed/27764191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164967 |
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