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Monocytic cell type-specific transcriptional induction of collagenase.

Interstitial collagenase (MMP-1), a metalloproteinase produced by resident and inflammatory cells during connective tissue turnover, cleaves type I collagen fibrils. This catalytic event is rate limiting in remodeling of tissues rich in fibrillar collagen such as the skin and lungs. The regulation o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Pierce, R A, Sandefur, S, Doyle, G A, Welgus, H G
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118620
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