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A link between c-Myc-mediated transcriptional repression and neoplastic transformation.

Recent studies indicate that the transcription factor c-Myc contributes to oncogenesis by altering the expression of genes involved in cell proliferation, but its precise function in neoplasia remains ambiguous. The ability of c-Myc to bind the sequence CAC(G/A)TG and transactivate appears to be lin...

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Detalhes bibliográficos
Main Authors: Lee, L A, Dolde, C, Barrett, J, Wu, C S, Dang, C V
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507233/
https://ncbi.nlm.nih.gov/pubmed/8601634
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