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Estimating glycosaminoglycan–protein interaction affinity: water dominates the specific antithrombin–heparin interaction
Glycosaminoglycan (GAG)–protein interactions modulate many important biological processes. Structure–function studies on GAGs may reveal probes and drugs, but their structural complexity and highly acidic nature confound such work. Productivity will increase if we are able to identify tight-binding...
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| Pubblicato in: | Glycobiology |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072149/ https://ncbi.nlm.nih.gov/pubmed/27496757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cww073 |
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