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Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis.

Cystic fibrosis (CF) is a common autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator gene. Recombinant adenoviruses have shown promise as vectors for transfer of CF transmembrane conductance regulator cDNA to airway epithelia and correction of the Cl- transp...

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Sparad:
I publikationen:J Clin Invest
Huvudupphov: Zabner, J, Ramsey, B W, Meeker, D P, Aitken, M L, Balfour, R P, Gibson, R L, Launspach, J, Moscicki, R A, Richards, S M, Standaert, T A
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118573
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