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Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis.

Cystic fibrosis (CF) is a common autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator gene. Recombinant adenoviruses have shown promise as vectors for transfer of CF transmembrane conductance regulator cDNA to airway epithelia and correction of the Cl- transp...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Zabner, J, Ramsey, B W, Meeker, D P, Aitken, M L, Balfour, R P, Gibson, R L, Launspach, J, Moscicki, R A, Richards, S M, Standaert, T A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118573
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