Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans.

Allelic variants of Fc gamma R confer distinct phagocytic capacities providing a mechanism for heritable susceptibility to immune complex disease. Human Fc gamma RIIa has two codominantly expressed alleles, R131 and H131, which differ substantially in their ability to ligate human IgG2. The Fc gamma...

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Detalhes bibliográficos
Main Authors: Salmon, J E, Millard, S, Schachter, L A, Arnett, F C, Ginzler, E M, Gourley, M F, Ramsey-Goldman, R, Peterson, M G, Kimberly, R P
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507190/
https://ncbi.nlm.nih.gov/pubmed/8636449
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