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Chromatin accessibility contributes to simultaneous mutations of cancer genes

Somatic mutations of many cancer genes tend to co-occur (termed co-mutations) in certain patterns during tumor initiation and progression. However, the genetic and epigenetic mechanisms that contribute to the co-mutations of these cancer genes have yet to be explored. Here, we systematically investi...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Shi, Yi, Su, Xian-Bin, He, Kun-Yan, Wu, Bing-Hao, Zhang, Bo-Yu, Han, Ze-Guang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071887/
https://ncbi.nlm.nih.gov/pubmed/27762310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35270
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