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Malignancy of Cancers and Synthetic Lethal Interactions Associated With Mutations of Cancer Driver Genes

The mutation status of cancer driver genes may correlate with different degrees of malignancy of cancers. The doubling time and multidrug resistance are 2 phenotypes that reflect the degree of malignancy of cancer cells. Because most of cancer driver genes are hard to target, identification of their...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Wang, Xiaosheng, Zhang, Yue, Han, Ze-Guang, He, Kun-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778998/
https://ncbi.nlm.nih.gov/pubmed/26937901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000002697
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