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SparRec: An effective matrix completion framework of missing data imputation for GWAS

Genome-wide association studies present computational challenges for missing data imputation, while the advances of genotype technologies are generating datasets of large sample sizes with sample sets genotyped on multiple SNP chips. We present a new framework SparRec (Sparse Recovery) for imputatio...

Ausführliche Beschreibung

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Veröffentlicht in:Sci Rep
Hauptverfasser: Jiang, Bo, Ma, Shiqian, Causey, Jason, Qiao, Linbo, Hardin, Matthew Price, Bitts, Ian, Johnson, Daniel, Zhang, Shuzhong, Huang, Xiuzhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071878/
https://ncbi.nlm.nih.gov/pubmed/27762341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35534
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