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Genotype imputation via matrix completion

Most current genotype imputation methods are model-based and computationally intensive, taking days to impute one chromosome pair on 1000 people. We describe an efficient genotype imputation method based on matrix completion. Our matrix completion method is implemented in MATLAB and tested on real d...

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Detalhes bibliográficos
Main Authors: Chi, Eric C., Zhou, Hua, Chen, Gary K., Del Vecchyo, Diego Ortega, Lange, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589539/
https://ncbi.nlm.nih.gov/pubmed/23233546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.145821.112
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