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Charge Distribution Fine-Tunes the Translocation of α-Helical Amphipathic Peptides across Membranes

Hundreds of cationic antimicrobial and cell-penetrating peptides (CPPs) form amphipathic α-helices when bound to lipid membranes. Here, we test two hypotheses for the differences in the ability of these peptides to translocate across membranes. The first, which we now call the hydrophobicity hypothe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Ablan, Francis D.O., Spaller, B. Logan, Abdo, Kaitlyn I., Almeida, Paulo F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071627/
https://ncbi.nlm.nih.gov/pubmed/27760360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.08.047
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