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Charged Antimicrobial Peptides Can Translocate across Membranes without Forming Channel-like Pores

How can highly charged, cationic antimicrobial peptides (AMPs) translocate across hydrophobic lipid bilayers despite the prohibitive energetic penalty to do so? A common explanation has been the formation of peptide-lined channels. However, for most AMPs, no structures of membrane pores have been fo...

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Vydáno v:Biophys J
Hlavní autor: Ulmschneider, Jakob P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510918/
https://ncbi.nlm.nih.gov/pubmed/28700927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.056
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