Expression of Twist2 is controlled by T-cell receptor signaling and determines the survival and death of thymocytes

Self-reactive thymocytes are eliminated by negative selection, whereas competent thymocytes survive by positive selection. The strength of the T-cell receptor (TCR) signal determines the fate of thymocytes undergoing either positive or negative selection. The TCR signal strength is relatively higher...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Oh, S, Oh, J, Lee, C, Jeon, S, Choi, J, Hwang, S, Lee, Y, Lee, H, Seong, R H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071571/
https://ncbi.nlm.nih.gov/pubmed/27391798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.68
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