The novel H(2)S donor 4‐carboxy‐phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium

BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S) modulates many pathophysiological processes, including inflammation and allergic reactions, in which mast cells act as major effector cells. IgE receptor (FcεRI) cross linking leads to an increase in intracellular calcium ([Ca(+2)](i)), a critical ste...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Autores principales: Marino, Alice, Martelli, Alma, Citi, Valentina, Fu, Ming, Wang, Rui, Calderone, Vincenzo, Levi, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071562/
https://ncbi.nlm.nih.gov/pubmed/27548075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13583
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