Fbxw7 Deletion Accelerates Kras(G12D)-Driven Pancreatic Tumorigenesis via Yap Accumulation()()()

Pancreatic cancers driven by KRAS mutations require additional mutations for tumor progression. The tumor suppressor FBXW7 is altered in pancreatic cancers, but its contribution to pancreatic tumorigenesis is unknown. To determine potential cooperation between Kras mutation and Fbxw7 inactivation in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neoplasia
Päätekijät: Zhang, Qiang, Zhang, Yaqing, Parsels, Joshua D., Lohse, Ines, Lawrence, Theodore S., Pasca di Magliano, Marina, Sun, Yi, Morgan, Meredith A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Neoplasia Press 2016
Aiheet:
Short communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071541/
https://ncbi.nlm.nih.gov/pubmed/27764699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.08.009
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