Fbxw7 Deletion Accelerates Kras(G12D)-Driven Pancreatic Tumorigenesis via Yap Accumulation()()()

Pancreatic cancers driven by KRAS mutations require additional mutations for tumor progression. The tumor suppressor FBXW7 is altered in pancreatic cancers, but its contribution to pancreatic tumorigenesis is unknown. To determine potential cooperation between Kras mutation and Fbxw7 inactivation in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neoplasia
Prif Awduron: Zhang, Qiang, Zhang, Yaqing, Parsels, Joshua D., Lohse, Ines, Lawrence, Theodore S., Pasca di Magliano, Marina, Sun, Yi, Morgan, Meredith A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2016
Pynciau:
Short communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071541/
https://ncbi.nlm.nih.gov/pubmed/27764699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.08.009
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