Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury.

Studies in the rat have pointed to a role for intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of acute tubular necrosis. These studies used antibodies, which may have nonspecific effects. We report that renal ICAM-1 mRNA levels and systemic levels of the cytokines IL-1 and TNF-alpha i...

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Autors principals: Kelly, K J, Williams, W W, Colvin, R B, Meehan, S M, Springer, T A, Gutierrez-Ramos, J C, Bonventre, J V
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507153/
https://ncbi.nlm.nih.gov/pubmed/8613529
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