Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.
Gene targeting was used to produce mice deficient in intercellular adhesion molecule 1 (ICAM-1) or CD54, an immunoglobulin-like cell adhesion molecule that binds beta 2 integrins. Homozygous deficient animals develop normally, are fertile, and have a moderate granulocytosis. The nature of the mutati...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8104338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8529 |
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