Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes.

We have generated a transgenic model consisting of both the human renin and human angiotensinogen genes to study further the role played by the renin-angiotensin system in regulating arterial pressure. Transgenic mice containing either gene alone were normotensive, whereas mice containing both genes...

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Detalhes bibliográficos
Main Authors: Merrill, D C, Thompson, M W, Carney, C L, Granwehr, B P, Schlager, G, Robillard, J E, Sigmund, C D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507152/
https://ncbi.nlm.nih.gov/pubmed/8613528
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