Slitrk Missense Mutations Associated with Neuropsychiatric Disorders Distinctively Impair Slitrk Trafficking and Synapse Formation

Slit- and Trk-like (Slitrks) are a six-member family of synapse organizers that control excitatory and inhibitory synapse formation by forming trans-synaptic adhesions with LAR receptor protein tyrosine phosphatases (PTPs). Intriguingly, genetic mutations of Slitrks have been associated with a multi...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Kang, Hyeyeon, Han, Kyung Ah, Won, Seoung Youn, Kim, Ho Min, Lee, Young-Ho, Ko, Jaewon, Um, Ji Won
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071332/
https://ncbi.nlm.nih.gov/pubmed/27812321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00104
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