Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTPσ Synaptic Adhesion and Intracellular Signaling Pathways

Neurotrophin-3 (NT-3) is a secreted neurotrophic factor that binds neurotrophin receptor tyrosine kinase C (TrkC), which in turn binds to presynaptic protein tyrosine phosphatase σ (PTPσ) to govern excitatory synapse development. However, whether and how NT-3 cooperates with the TrkC-PTPσ synaptic a...

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Publicat a:J Neurosci
Autors principals: Han, Kyung Ah, Woo, Doyeon, Kim, Seungjoon, Choii, Gayoung, Jeon, Sangmin, Won, Seoung Youn, Kim, Ho Min, Heo, Won Do, Um, Ji Won, Ko, Jaewon
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601719/
https://ncbi.nlm.nih.gov/pubmed/27122038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4024-15.2016
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