Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline.

Angiotensin I-converting enzyme (ACE) has two homologous active NH2- and COOH-terminal domains and displays activity toward a broad range of substrates. The tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) has been shown to be hydrolyzed in vitro by ACE and to be a preferential substrate...

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Detalhes bibliográficos
Main Authors: Azizi, M, Rousseau, A, Ezan, E, Guyene, T T, Michelet, S, Grognet, J M, Lenfant, M, Corvol, P, Ménard, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507123/
https://ncbi.nlm.nih.gov/pubmed/8609242
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