Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension

Fibrosis is an important component of large conduit artery disease in hypertension. The endogenous tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) has anti-inflammatory and antifibrotic effects in the heart and kidney. However, it is not known whether Ac-SDKP has an anti-inflammatory an...

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Detalhes bibliográficos
Main Authors: Lin, Chun-Xia, Rhaleb, Nour-Eddine, Yang, Xiao-Ping, Liao, Tang-Dong, D'Ambrosio, Martin A., Carretero, Oscar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544498/
https://ncbi.nlm.nih.gov/pubmed/18641275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00481.2008
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