A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22

A unique feature of rheumatoid arthritis (RA) is the presence of anti-citrullinated protein antibodies (ACPA). Several risk factors for RA are known to increase the expression or activity of peptidyl arginine deiminases (PADs), which catalyze citrullination and, when dysregulated, can result in hype...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Chang, Hui-Hsin, Liu, Guang-Yaw, Dwivedi, Nishant, Sun, Bo, Okamoto, Yuko, Kinslow, Jennifer D., Deane, Kevin D., Demoruelle, M. Kristen, Norris, Jill M., Thompson, Paul R., Sparks, Jeffrey A., Rao, Deepak A., Karlson, Elizabeth W., Hung, Hui-Chih, Holers, V. Michael, Ho, I-Cheng
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070957/
https://ncbi.nlm.nih.gov/pubmed/27777982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90045
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