Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis

Mouse models lupus nephritis (LN) have provided important insights into disease pathogenesis, although none have been able to recapitulate all features of the human disease. Using comprehensive longitudinal analyses, we characterized a novel accelerated mouse model of lupus using pristane treatment...

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發表在:PLoS One
Main Authors: Gardet, Agnes, Chou, Wei C., Reynolds, Taylor L., Velez, Diana B., Fu, Kai, Czerkowicz, Julia M., Bajko, Jeffrey, Ranger, Ann M., Allaire, Normand, Kerns, Hannah M., Ryan, Sarah, Legault, Holly M., Dunstan, Robert W., Lafyatis, Robert, Lukashev, Matvey, Viney, Joanne L., Browning, Jeffrey L., Rabah, Dania
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070861/
https://ncbi.nlm.nih.gov/pubmed/27760209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164423
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