Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly

STUDY OBJECTIVES: Emerging evidence suggests a role for sleep in contributing to the progression of Alzheimer disease (AD). Slow wave sleep (SWS) is the stage during which synaptic activity is minimal and clearance of neuronal metabolites is high, making it an ideal state to regulate levels of amylo...

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Publicat a:Sleep
Autors principals: Varga, Andrew W., Wohlleber, Margaret E., Giménez, Sandra, Romero, Sergio, Alonso, Joan F., Ducca, Emma L., Kam, Korey, Lewis, Clifton, Tanzi, Emily B., Tweardy, Samuel, Kishi, Akifumi, Parekh, Ankit, Fischer, Esther, Gumb, Tyler, Alcolea, Daniel, Fortea, Juan, Lleó, Alberto, Blennow, Kaj, Zetterberg, Henrik, Mosconi, Lisa, Glodzik, Lidia, Pirraglia, Elizabeth, Burschtin, Omar E., de Leon, Mony J., Rapoport, David M., Lu, Shou-en, Ayappa, Indu, Osorio, Ricardo S.
Format: Artigo
Idioma:Inglês
Publicat: Associated Professional Sleep Societies, LLC 2016
Matèries:
Sleep and Aging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070758/
https://ncbi.nlm.nih.gov/pubmed/27568802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.6240
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