Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects

STUDY OBJECTIVES: To evaluate the role of orexin-A with respect to cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers, and explore its relationship to cognition and sleep characteristics in a group of cognitively normal elderly individuals. METHODS: Subjects were recruited from multiple com...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Osorio, Ricardo S., Ducca, Emma L., Wohlleber, Margaret E., Tanzi, Emily B., Gumb, Tyler, Twumasi, Akosua, Tweardy, Samuel, Lewis, Clifton, Fischer, Esther, Koushyk, Viachaslau, Cuartero-Toledo, Maria, Sheikh, Mohammed O., Pirraglia, Elizabeth, Zetterberg, Henrik, Blennow, Kaj, Lu, Shou-En, Mosconi, Lisa, Glodzik, Lidia, Schuetz, Sonja, Varga, Andrew W., Ayappa, Indu, Rapoport, David M., de Leon, Mony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2016
Assuntos:
Neurological Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863214/
https://ncbi.nlm.nih.gov/pubmed/26951396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5846
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