Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly

STUDY OBJECTIVES: Emerging evidence suggests a role for sleep in contributing to the progression of Alzheimer disease (AD). Slow wave sleep (SWS) is the stage during which synaptic activity is minimal and clearance of neuronal metabolites is high, making it an ideal state to regulate levels of amylo...

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Foilsithe in:Sleep
Main Authors: Varga, Andrew W., Wohlleber, Margaret E., Giménez, Sandra, Romero, Sergio, Alonso, Joan F., Ducca, Emma L., Kam, Korey, Lewis, Clifton, Tanzi, Emily B., Tweardy, Samuel, Kishi, Akifumi, Parekh, Ankit, Fischer, Esther, Gumb, Tyler, Alcolea, Daniel, Fortea, Juan, Lleó, Alberto, Blennow, Kaj, Zetterberg, Henrik, Mosconi, Lisa, Glodzik, Lidia, Pirraglia, Elizabeth, Burschtin, Omar E., de Leon, Mony J., Rapoport, David M., Lu, Shou-en, Ayappa, Indu, Osorio, Ricardo S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Associated Professional Sleep Societies, LLC 2016
Ábhair:
Sleep and Aging
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070758/
https://ncbi.nlm.nih.gov/pubmed/27568802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.6240
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