Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

Peripheral T-cell lymphomas (PTCLs) are aggressive malignancies of mature T lymphocytes with 5-year overall survival rates of only ∼ 35%. Improvement in outcomes has been stymied by poor understanding of the genetics and molecular pathogenesis of PTCL, with a resulting paucity of molecular targets f...

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Publicado en:Blood
Main Authors: Vasmatzis, George, Johnson, Sarah H., Knudson, Ryan A., Ketterling, Rhett P., Braggio, Esteban, Fonseca, Rafael, Viswanatha, David S., Law, Mark E., Kip, N. Sertac, Özsan, Nazan, Grebe, Stefan K., Frederick, Lori A., Eckloff, Bruce W., Thompson, E. Aubrey, Kadin, Marshall E., Milosevic, Dragana, Porcher, Julie C., Asmann, Yan W., Smith, David I., Kovtun, Irina V., Ansell, Stephen M., Dogan, Ahmet, Feldman, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070713/
https://ncbi.nlm.nih.gov/pubmed/22855598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-419937
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