Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

Peripheral T-cell lymphomas (PTCLs) are aggressive malignancies of mature T lymphocytes with 5-year overall survival rates of only ∼ 35%. Improvement in outcomes has been stymied by poor understanding of the genetics and molecular pathogenesis of PTCL, with a resulting paucity of molecular targets f...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Blood
Κύριοι συγγραφείς: Vasmatzis, George, Johnson, Sarah H., Knudson, Ryan A., Ketterling, Rhett P., Braggio, Esteban, Fonseca, Rafael, Viswanatha, David S., Law, Mark E., Kip, N. Sertac, Özsan, Nazan, Grebe, Stefan K., Frederick, Lori A., Eckloff, Bruce W., Thompson, E. Aubrey, Kadin, Marshall E., Milosevic, Dragana, Porcher, Julie C., Asmann, Yan W., Smith, David I., Kovtun, Irina V., Ansell, Stephen M., Dogan, Ahmet, Feldman, Andrew L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2012
Θέματα:
Lymphoid Neoplasia
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070713/
https://ncbi.nlm.nih.gov/pubmed/22855598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-419937
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