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Potentiation of TRAIL killing activity by multimerization through isoleucine zipper hexamerization motif

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a homo-trimeric cytotoxic ligand. Several studies have demonstrated that incorporation of artificial trimerization motifs into the TRAIL protein leads to the enhancement of biological activity. Here, we show that linkage of the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMB Rep
मुख्य लेखकों: Han, Ji Hye, Moon, Ae Ran, Chang, Jeong Hwan, Bae, Jeehyeon, Choi, Jin Myung, Lee, Sung Haeng, Kim, Tae-Hyoung
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Korean Society for Biochemistry and Molecular Biology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070708/
https://ncbi.nlm.nih.gov/pubmed/26674343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.5.245
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