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Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells

Recent evidence indicates that cancer cells, even in the absence of a primary tumor, recirculate from established secondary lesions to further seed and colonize skeleton and soft-tissues, thus expanding metastatic dissemination and precipitating the clinical progression to terminal disease. Recently...

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Détails bibliographiques
Publié dans:Mol Cancer Res
Auteurs principaux: Shen, Fei, Zhang, Yun, Jernigan, Danielle L., Feng, Xin, Yan, Jie, Garcia, Fernando U., Meucci, Olimpia, Salvino, Joseph M., Fatatis, Alessandro
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070649/
https://ncbi.nlm.nih.gov/pubmed/27001765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0013
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