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Genetic Screening and Analysis of LKB1 Gene in Chinese Patients with Peutz-Jeghers Syndrome

BACKGROUND: Peutz-Jeghers syndrome (PJS) is an autosomal dominant genetic disease. It severely decreases patient quality of life and leads elevated cancer risk. Germline mutation of LKB1 is the leading cause of familial PJS. MATERIAL/METHODS: To characterize the germline mutation of LKB1 gene in Chi...

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Dades bibliogràfiques
Publicat a:Med Sci Monit
Autors principals: Chen, Chunyan, Zhang, Xiaomei, Wang, Deqiang, Wang, Fangyu, Pan, Jian, Wang, Zhenkai, Liu, Chang, Wu, Lin, Lu, Heng, Li, Nan, Wei, Juan, Shi, Hui, Wan, Haijun, Zhu, Ming, Chen, Senqing, Zhou, Yun, Zhou, Xin, Yang, Liu, Liu, Jiong
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2016
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070620/
https://ncbi.nlm.nih.gov/pubmed/27721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897498
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