How Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal Data

BACKGROUND AND OBJECTIVE: To clarify mechanisms of genetic regulation of human aging and longevity traits, a number of genome-wide association studies (GWAS) of these traits have been performed. However, the results of these analyses did not meet expectations of the researchers. Most detected geneti...

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Vydáno v:N Am Actuar J
Hlavní autoři: Yashin, Anatoliy I., Arbeev, Konstantin G., Wu, Deqing, Arbeeva, Liubov, Kulminski, Alexander, Kulminskaya, Irina, Akushevich, Igor, Ukraintseva, Svetlana V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070546/
https://ncbi.nlm.nih.gov/pubmed/27773987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10920277.2016.1178588
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