V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Synthetic Modified mRNA Drives Reprogramming of Human Pancreatic Duct-Derived Cells Into Insulin-Secreting Cells

β-Cell replacement therapy represents the most promising approach to restore β-cell mass and glucose homeostasis in patients with type 1 diabetes. Safety and ethical issues associated with pluripotent stem cells stimulated the search for adult progenitor cells with endocrine differentiation capaciti...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Corritore, Elisa, Lee, Yong-Syu, Pasquale, Valentina, Liberati, Daniela, Hsu, Mei-Ju, Lombard, Catherine Anne, Van Der Smissen, Patrick, Vetere, Amedeo, Bonner-Weir, Susan, Piemonti, Lorenzo, Sokal, Etienne, Lysy, Philippe A.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Enabling Technologies for Cell-Based Clinical Translation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070501/
https://ncbi.nlm.nih.gov/pubmed/27405779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0318
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