Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study

BACKGROUND: Triple-negative breast cancer (TNBC) with a BRCA1-like molecular signature has been demonstrated to remarkably respond to platinum-based chemotherapy and might be suited for a future treatment with poly(ADP-ribose)polymerase (PARP) inhibitors. In order to rapidly assess this signature we...

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書誌詳細
出版年:BMC Cancer
主要な著者: Gross, Eva, van Tinteren, Harm, Li, Zhou, Raab, Sandra, Meul, Christina, Avril, Stefanie, Laddach, Nadja, Aubele, Michaela, Propping, Corinna, Gkazepis, Apostolos, Schmitt, Manfred, Meindl, Alfons, Nederlof, Petra M., Kiechle, Marion, Lips, Esther H.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070367/
https://ncbi.nlm.nih.gov/pubmed/27756336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2848-2
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