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A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide.

A unique screen was used to identify mutations in Escherichia coli lipid A biosynthesis that result in a decreased ability to stimulate E-selectin expression by human endothelial cells. A mutation was identified in the msbB gene of E. coli that resulted in lipopolysaccharide (LPS) that lacks the myr...

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Bibliografiske detaljer
Main Authors: Somerville, J E, Cassiano, L, Bainbridge, B, Cunningham, M D, Darveau, R P
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507025/
https://ncbi.nlm.nih.gov/pubmed/8567955
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