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Escherichia coli msbB Gene as a Virulence Factor and a Therapeutic Target

A mutation in the msbB gene of Escherichia coli results in the synthesis of E. coli lipopolysaccharide (LPS) that lacks the myristic acid moiety of lipid A. Although such mutant E. coli cells and their purified LPS have a greatly reduced ability to stimulate human immune cells, a minor reduction in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Somerville, John E., Cassiano, Linda, Darveau, Richard P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97070/
https://ncbi.nlm.nih.gov/pubmed/10569778
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