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Interleukin 7 receptor functions by recruiting the tyrosine kinase p59fyn through a segment of its cytoplasmic tail.

Engagement of the cell surface receptor for interleukin 7 (IL-7R) provokes protein tyrosine phosphorylation, although the receptor lacks a kinase catalytic domain in its cytoplasmic tail. The molecular basis of this response is not known. Here we report that the IL-7R functions by recruiting p59fyn,...

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Hlavní autoři: Venkitaraman, A R, Cowling, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC50702/
https://ncbi.nlm.nih.gov/pubmed/1465444
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