Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

BACKGROUND: The value of KI67 in breast cancer prognostication has been questioned due to concerns on the analytical validity of visual KI67 assessment and methodological limitations of published studies. Here, we investigate the prognostic value of automated KI67 scoring in a large, multicentre stu...

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Pubblicato in:Breast Cancer Res
Autori principali: Abubakar, Mustapha, Orr, Nick, Daley, Frances, Coulson, Penny, Ali, H. Raza, Blows, Fiona, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang-Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J., Devilee, Peter, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Figueroa, Jonine, Sherman, Mark E., Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., Investigators, kConFab, Bolla, Manjeet K., Wang, Qin, Jones, Michael, Schoemaker, Minouk, Wesseling, Jelle, van Leeuwen, Flora E., Van ‘t Veer, Laura, Easton, Douglas, Swerdlow, Anthony J., Dowsett, Mitch, Pharoah, Paul D., Schmidt, Marjanka K., Garcia-Closas, Montserrat
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070183/
https://ncbi.nlm.nih.gov/pubmed/27756439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0765-6
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