Lung-Restricted Antibodies Mediate Primary Graft Dysfunction and Prevent Allotolerance after Murine Lung Transplantation

Over one-third of lung recipients have preexisting antibodies against lung-restricted antigens: collagen (Col) type V and K-α1 tubulin (KAT). Although clinical studies have shown association of these antibodies with primary graft dysfunction (PGD), their biological significance remains unclear. We t...

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Publicado en:Am J Respir Cell Mol Biol
Autores principales: Bharat, Ankit, Chiu, Stephen, Zheng, Zhikun, Sun, Haiying, Yeldandi, Anjana, DeCamp, Malcolm M., Perlman, Harris, Budinger, G. R. Scott, Mohanakumar, Thalachallour
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2016
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070112/
https://ncbi.nlm.nih.gov/pubmed/27144500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0077OC
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