Lung injury combined with loss of regulatory T cells leads to de novo lung-restricted autoimmunity

Over one-third of patients with chronic lung disease undergoing lung transplantation have pre-existing antibodies against lung-restricted self-antigens, collagen type V (ColV) and k-alpha1 tubulin (KAT). These antibodies can also develop de novo following lung transplantation and mediate allograft r...

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Detalhes bibliográficos
Publicado no:J Immunol
Principais autores: Chiu, Stephen, Fernandez, Ramiro, Subramanian, Vijay, Sun, Haiying, DeCamp, Malcolm M, Kreisel, Daniel, Perlman, Harris, Budinger, G.R. Scott, Mohanakumar, Thalachallour, Bharat, Ankit
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912911/
https://ncbi.nlm.nih.gov/pubmed/27194786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502539
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