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Neonatal Lethality, Dwarfism, and Abnormal Brain Development in Dmbx1 Mutant Mice

Dmbx1 encodes a paired-like homeodomain protein that is expressed in developing neural tissues during mouse embryogenesis. To elucidate the in vivo role of Dmbx1, we generated two Dmbx1 mutant alleles. Dmbx1(−) lacks the homeobox and Dmbx1(z) is an insertion of a lacZ reporter gene. Dmbx1(z) appears...

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Detalhes bibliográficos
Main Authors: Ohtoshi, Akihira, Behringer, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507007/
https://ncbi.nlm.nih.gov/pubmed/15314164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7548-7558.2004
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