Single-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways

The effects of estrogens, particularly 17β-estradiol (E2), are mediated by estrogen receptor α (ERα) and ERβ. Upon binding to E2, ERs homo- and heterodimerize when coexpressed. The ER dimer then regulates the transcription of target genes through estrogen responsive element (ERE)-dependent and -inde...

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Autores principales: Li, Xiaodong, Huang, Jing, Yi, Ping, Bambara, Robert A., Hilf, Russell, Muyan, Mesut
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC506997/
https://ncbi.nlm.nih.gov/pubmed/15314175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7681-7694.2004
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