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Role of an mSin3A-Swi/Snf Chromatin Remodeling Complex in the Feedback Repression of Bile Acid Biosynthesis by SHP

The orphan receptor SHP interacts with many nuclear receptors and inhibits their transcriptional activities. SHP is central to feedback repression of cholesterol 7α hydroxylase gene (CYP7A1) expression by bile acids, which is critical for maintaining cholesterol homeostasis. Using CYP7A1 as a model...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Kemper, Jongsook Kim, Kim, Hwajin, Miao, Ji, Bhalla, Sonali, Bae, Yangjin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC506991/
https://ncbi.nlm.nih.gov/pubmed/15314177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7707-7719.2004
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